What is the difference between progesterone and medroxyprogesterone

Postcoital contraception, or emergency contraception, has been found to reduce the rates of unwanted pregnancy after unprotected sexual intercourse, with no significant adverse outcomes. It is estimated that post-coital contraception can prevent about 75 percent of pregnancies that would occur without treatment. The only WHO contraindication to the use of emergency contraception is pregnancy. Contraindications from the U. Food and Drug Administration FDA include coronary artery disease, clotting disorders and a history of venous thromboembolism.

Because of the high estrogen doses, nausea, vomiting, dizziness and fatigue are common side effects. Compared with the Yuzpe method, a progestin-only method has been found to have lower rates of side effects and greater efficacy 85 percent pregnancy prevention rate for the progestin-only method versus 57 percent pregnancy prevention rate for the Yuzpe method.

One tablet is taken as soon as possible but no later than 72 hours after unprotected sexual intercourse; the second tablet is taken 12 hours after the first dose.

Already a member or subscriber? Log in. Interested in AAFP membership? Learn more. In addition, Dr. Greenberg also earned a master's degree in ecology and evolutionary biology at Indiana University, Bloomington. Address correspondence to Barbara S. Apgar, M. Reprints are not available from the authors. Bioavailability of progesterone with different modes of administration.

J Reprod Med. Simon JA. Micronized progesterone: vaginal and oral uses. Clin Obstet Gynecol. Fraser IS. Regulating menstrual bleeding. A prime function of progesterone. Giudice LC. Genes associated with embryonic attachment and implantation and the role of progesterone. Ferenczy A, Gelfand M.

The biologic significance of cytologic atypia in progesterone-treated endometrial hyperplasia. Am J Obstet Gynecol. Progestin treatment of atypical hyperplasia and well-differentiated carcinoma of the endometrium in women under age Obstet Gynecol.

Peterson CM. Progestogens, progesterone antagonists, progesterone, and androgens: synthesis, classification, and uses. The absorption of oral micronized progesterone: the effect of food, dose proportionality, and comparison with intramuscular progesterone. Fertil Steril. Sherwin BB. The impact of different doses of estrogen and progestin on mood and sexual behavior in postmenopausal women.

J Clin Endocrinol Metab. Subfractions of high-density lipoprotein cholesterol during estrogen replacement therapy: a comparison between progestogens and natural progesterone. Pregnancies following ovum donation in gonadal dysgenesis. Hum Reprod. Transvaginal administration of progesterone. Oral contraception. In: Clinical gynecologic endocrinology and infertility. Collins DC. Sex hormone receptor binding, progestin selectivity, and the new oral contraceptives. No adverse effects of medroxyprogesterone treatment without estrogen in postmenopausal women: double-blind, placebo-controlled, crossover trial.

Factors associated with withdrawal bleeding after administration of oral dydrogesterone or medroxyprogesterone acetate in women with secondary amenorrhea. Gynecol Obstet Invest. Factors associated with withdrawal bleeding after administration of oral micronized progesterone in women with secondary amenorrhea. Dysfunctional uterine bleeding. Sequential use of norethisterone and natural progesterone in premenopausal bleeding disorders.

Dysfunctional uterine bleeding in adolescents. The role and use of progestogens. The behavior of endometrial hyperplasia.

Hormone replacement therapy and endometrial cancer risk: a meta-analysis. Induction of amenorrhea during hormone replacement therapy: optimal micronized progesterone dose. A comparison of mechanisms underlying disturbances of bleeding caused by spontaneous dysfunctional uterine bleeding or hormonal contraception. The use of levonorgestrel implants Norplant for contraception in adolescent mothers. N Engl J Med. Lidegaard O.

Oral contraception and risk of a cerebral thromboembolic attack: results of a case-control study. Risk of venous thrombosis with use of current low-dose oral contraceptives is not explained by diagnostic suspicion and referral bias.

Arch Intern Med. Estimates of the risk of cardiovascular death attributable to low-dose oral contraceptives in the United States. Winkler UH. Effects on hemostatic variables of desogestrel- and gestodene-containing oral contraceptives in comparison with levonorgestrel-containing oral contraceptives: a review. Randomised controlled trial of levonorgestrel versus the Yuzpe regimen of combined oral contraceptives for emergency contraception. The effectiveness of the Yuzpe regimen of emergency contraception.

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Purchase Access: See My Options close. Best Value! To see the full article, log in or purchase access. More in Pubmed Citation Related Articles. Email Alerts Don't miss a single issue. Sign up for the free AFP email table of contents. Navigate this Article. Ethynodiol diacetate with ethinyl estradiol: Demulen. Norethindrone Micronor. Norethindrone acetate Aygestin. Levonorgestrel Norplant; with ethinyl estradiol: Alesse, Nordette.

Medroxyprogesterone acetate Provera. Natural micronized progesterone. Synthetic progestins. Medroxyprogesterone acetate. Induction of secretory endometrium. Vial or prefilled syringe, for IM injection. Norethindrone acetate. They follow accepted methods of physical and surgical diagnoses and treatments, and stress the unity of all body systems. These physicians emphasize the musculoskeletal system, holistic medicine, proper nutrition and the effects of environmental factors.

Today, D. Like many things, diagnostic X-rays have risks as well as benefits. They should be used only when they will give the doctor information needed to treat you. You will probably not need any abdominal X-rays during pregnancy; however, because of a number of medical conditions, your physician may feel that a diagnostic X-ray of your abdomen or lower torso is needed. If this should happen, there is no reason to be upset.

The risk to you and your unborn child is very small and the benefit of finding out about your medical conditions is far greater. Actually, the risk of not having a needed X-ray could be much greater than the risk from radiation. Even small risks, such as radiation from X-rays, should be avoided during pregnancy. You can reduce these risks by telling your doctor that you are pregnant or you think that you might be.

If you are pregnant, your doctor may decide to cancel or postpone the X-ray or modify it to reduce the amount of radiation. Depending on your medical needs, the doctor may decide that it is best to proceed with the X-ray as planned. During most X-ray examinations, such as those for arms, legs, teeth, or chest, your reproductive organs are not exposed to the direct X-ray beam.

These procedures when done properly do not involve any risk to the unborn child. These diagnostic X-rays are of more concern. It is known that the unborn child is very sensitive to the effects of things like radiation, certain drugs, excess alcohol and infections.

One reason is that the cells of the embryo are rapidly dividing and growing into specialized cells and tissues. If radiation or other agents were to cause changes in these cells, there could be a slightly increased chance of birth defect of certain illnesses, like leukemia, later in life.

There is scientific disagreement about whether the small amounts of radiation used in diagnostic radiology can actually harm the unborn child. The majority of birth defects and childhood diseases occur even if the mother is not exposed to any known harmful agent during pregnancy.

Scientists think that heredity and random errors in the developmental process are responsible for most of these problems. What are Bio-Identical Hormones? Unless discussed with your doctor, avoid ibuprofen Motrin, Advil as well as naproxen Aleve Should I register for cord blood donation? What is Estrogen? How do the physiological effects of estrogen and progesterone compare to each other?

What is the difference between Progesterone and Synthetic Progestins provera or medroxyprogesterone? What is a D. What About X-Rays and Pregnancy? How do X-rays affect the unborn child? Gynecological Services more info. Obstetrical Services more info. Pap Smear and Colposcopy more info. Birth Control more info. Genetic Testing more info. Surgical Services more info.